Synthesis, Antimicrobial and Binding Interaction Study of Novel Piperamides with Bovine Serum Albumin
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Synthesis of Three Rimantadine Schiff Bases and Their Biological Effects on Serum Albumin
Three new rimantadine Schiff bases (RSBs) were prepared, and then the interaction of RSBs with bovine serum albumin (BSA) was investigated using fluorescence, synchronous fluorescence, UV-vis absorption spectroscopy under physiological conditions. The results showed that the three RSBs effectively quenched the intrinsic fluorescence of BSA via static quenching. Binding constant (Ka), number of ...
متن کاملSynthesis of Three Rimantadine Schiff Bases and Their Biological Effects on Serum Albumin
Three new rimantadine Schiff bases (RSBs) were prepared, and then the interaction of RSBs with bovine serum albumin (BSA) was investigated using fluorescence, synchronous fluorescence, UV-vis absorption spectroscopy under physiological conditions. The results showed that the three RSBs effectively quenched the intrinsic fluorescence of BSA via static quenching. Binding constant (Ka), number of ...
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